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Joseph Gleave was educated at Manchester Grammar School and trained at Manchester University School of Architecture whilst being articled to Theo halliday between 1923-1927. He worked in Nottingham for a while as an assistant to T.C. Howitt. In 1930 he set up a small practice in Manchester. At this time he was involved in the International Columbus Memorial Competition which he won. In 1935 he moved to Edinburgh to join the teaching staff at Edinburgh College of Art eventually becoming Head of the Department of Architecture and Town Planning from 1935 to 1948. He worked for almost a year in the Dominincan Republic on the Columbus project between 1948 and 1949 and in 1950 he went to Glasgow and joined the architect Graham Henderson forming the practice Keppie, Henderson and Gleave and specialising in hospital design. In 1958 he set up his own Glasgow practice J.L. Gleave and Partners. He exhibited at the RSA from 1934 until 1962. He became an Associate Member of the RSA in 1953 and an Academician in 1959.